Background:

This gene encodes a member of a subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal suppressor of cytokine signaling (SOCS) box. This protein plays a role in cell signaling. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

SPSB2

Immunogen:

Fusion protein of human SPSB2

Full name:

splA/ryanodine receptor domain and SOCS box containing 2

Synonyms:

SSB2; GRCC9

SwissProt:

Q99619

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-100