Background:

This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.

Applications:

WB, IHC, IF

Name of antibody:

MRC2

Immunogen:

Synthesized peptide derived from internal of human MRC2.

Full name:

mannose receptor, C type 2

Synonyms：

CD280; UPARAP; CLEC13E; ENDO180

SwissProt:

Q9UBG0

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

167 kDa

WB Positive control:

293 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

HepG2 cells

IF Recommend dilution:

100-500