Background:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export.

Applications:

WB

Name of antibody:

NFKBIA(Phospho-Tyr305)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine 305 (L-P-Y(p)-D-D) derived from Human I kappaB- alpha.

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Synonyms：

IKBA; MAD-3; NFKBI

SwissProt:

P25963

WB Predicted band size:

36 kDa

WB Positive control:

COS7 cells lysates

WB Recommended dilution:

500-1000