Background:

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Applications:

WB, IF

Name of antibody:

NDC80

Immunogen:

Synthesized peptide derived from internal of human KNTC2.

Full name:

NDC80 kinetochore complex component

Synonyms：

HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80

SwissProt:

O14777

WB Predicted band size:

74 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Huvec cells

IF Recommend dilution:

100-500