Background:

The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

PICK1

Immunogen:

Synthetic peptide of human PICK1

Full name:

protein interacting with PRKCA 1

Synonyms：

PICK; PRKCABP

SwissProt:

Q9NRD5

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

25-100