Background:

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.

Applications:

ELISA, IHC

Name of antibody:

VPS35

Immunogen:

Fusion protein of human VPS35

Full name:

VPS35 retromer complex component

Synonyms:

MEM3; PARK17

SwissProt:

Q96QK1

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

30-150