Background:

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.

Applications:

WB

Name of antibody:

VRK3

Immunogen:

Synthesized peptide derived from Internal of human VRK3.

Full name:

vaccinia related kinase 3

Synonyms：

0

SwissProt:

Q8IV63

WB Predicted band size:

53 kDa

WB Positive control:

COLO205 cells lysate

WB Recommended dilution:

500-3000