Background:

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.

Applications:

ELISA, IHC

Name of antibody:

SFRP2

Immunogen:

Synthetic peptide of human SFRP2

Full name:

secreted frizzled related protein 2

Synonyms:

FRP-2; SARP1; SDF-5

SwissProt:

Q96HF1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100