Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3.

Applications:

WB

Name of antibody:

MRPL14

Immunogen:

Synthesized peptide derived from internal of human MRPL14.

Full name:

mitochondrial ribosomal protein L14

Synonyms：

L14mt; L32mt; MRPL32; RMPL32; RPML32; MRP-L14; MRP-L32

SwissProt:

Q6P1L8

WB Predicted band size:

16 kDa

WB Positive control:

Hela cells, COLO cells and 293 cells lysates

WB Recommended dilution:

500-3000