Background:

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum.

Applications:

WB

Name of antibody:

SREBF1(Phospho-Ser439)

Immunogen:

Peptide sequence around phosphorylation site of serine439(Q-S-S(p)-P-L) derived from Human SREBP-1 .

Full name:

sterol regulatory element binding transcription factor 1

Synonyms：

SREBP1; bHLHd1; SREBP-1c

SwissProt:

P36956

WB Predicted band size:

122 kDa

WB Positive control:

Jurkat cells lysates treated with TNF

WB Recommended dilution:

500-1000