Background:

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.

Applications:

ELISA, IHC

Name of antibody:

SLC6A3

Immunogen:

Synthetic peptide of human SLC6A3

Full name:

solute carrier family 6 member 3

Synonyms:

DAT; DAT1; PKDYS; PKDYS1

SwissProt:

Q01959

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human brain

IHC Recommend dilution:

50-200