Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B.

Applications:

WB

Name of antibody:

MAP2K7(Ab-271)

Immunogen:

Synthesized non-phosphopeptide derived from human MAP2K7 around the phosphorylation site of serine 271 (V-D-S(p)-K-A).

Full name:

mitogen-activated protein kinase kinase kinase 7

Synonyms：

TAK1; MEKK7; TGF1a

SwissProt:

O43318

WB Predicted band size:

67 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000