Background:

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

MLXIPL

Immunogen:

Synthetic peptide of human MLXIPL

Full name:

MLX interacting protein-like

Synonyms:

MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14

SwissProt:

Q9NP71

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

20-100