Background:

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Applications:

ELISA, IHC

Name of antibody:

SIPA1

Immunogen:

Synthetic peptide of human SIPA1

Full name:

signal-induced proliferation-associated 1

Synonyms：

SPA1

SwissProt:

Q96FS4

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human cervical cancer

IHC Recommend dilution:

50-200