Background:

This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications:

ELISA, IHC

Name of antibody:

STXBP2

Immunogen:

Fusion protein of human STXBP2

Full name:

syntaxin binding protein 2

Synonyms：

FHL5; UNC18B; Hunc18b; UNC18-2; pp10122; MUNC18-2

SwissProt:

Q15833

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

25-100