Background:

Eosinophil Cationic Protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the eosinophil cationic protein is encoded by the RNASE3 gene. ECP is released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body. There are three glycosolated forms of ECP and consequently ECP has a range of molecular weights from 18-22 kDa

Applications:

ELISA, WB, IHC

Name of antibody:

RNASE3

Immunogen:

Fusion protein of human RNASE3

Full name:

ribonuclease, RNase A family, 3

Synonyms：

ECP; RNS3

SwissProt:

P12724

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

18 kDa

WB Positive control:

U937 cells

WB Recommended dilution:

200-1000