Background:

The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.

Applications:

ELISA, WB, IHC

Name of antibody:

SLC22A6

Immunogen:

Synthetic peptide of human SLC22A6

Full name:

Solute carrier family 22 (organic anion transporter), member 6

Synonyms：

OAT1, PAHT, HOAT1, ROAT1

SwissProt:

Q4U2R8

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human colon cancer and Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

56 kDa

WB Positive control:

Human fetal kidney tissue

WB Recommended dilution:

500-2000