Background:

This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus.

Applications:

ELISA, IHC

Name of antibody:

PIF1

Immunogen:

Synthetic peptide of human PIF1

Full name:

PIF1 5'-to-3' DNA helicase

Synonyms：

PIF; C15orf20

SwissProt:

Q9H611

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100