Background:

SCRN genes encode protein members of the secernin family including Secernin 1, Secernin 2 and Secernin 3. Function of Secernin 2 and Secernin 3 are so far not well understood. Secernin 1 is a novel 50-kDa cytosolic protein that appears to be involved in the regulation of exocytosis from peritoneal mast cells. Secernin-1 a novel tumor-associated antigen (TAA) and may be a universal marker of different cancer types including gastric cancer, which has been validated by several researches. Measurement of SCRN1 can be used in the early detection of cancer or in the surveillance of patients who undergo surgery.

Applications:

ELISA, WB, IHC

Name of antibody:

SCRN2

Immunogen:

Fusion protein of human SCRN2

Full name:

secernin 2

Synonyms:

Ses2

SwissProt:

Q96FV2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human tonsil

IHC Recommend dilution:

50-300

WB Predicted band size:

47 kDa

WB Positive control:

Mouse small intestines tissue lysate

WB Recommended dilution:

500-2000