Background:

This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Applications:

ELISA, IHC

Name of antibody:

PF4

Immunogen:

Synthetic peptide of human PF4

Full name:

platelet factor 4

Synonyms：

PF-4; CXCL4; SCYB4

SwissProt:

P02776

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human colorectal cancer

IHC Recommend dilution:

25-100