Background:

The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011]

Applications:

ELISA, WB, IHC

Name of antibody:

POLB

Immunogen:

Fusion protein of human POLB

Full name:

DNA polymerase beta

SwissProt:

P06746

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human gastric cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

38 kDa

WB Positive control:

Jurkat cell lysate

WB Recommended dilution:

500-2000