Background:

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

NCR3

Immunogen:

Fusion protein of human NCR3

Full name:

natural cytotoxicity triggering receptor 3

Synonyms：

1C7; MALS; CD337; LY117; NKp30

SwissProt:

O14931

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200