Background:

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

Applications:

WB, IHC

Name of antibody:

PTK2(Ab-843)

Immunogen:

Synthesized peptide derived from Internal of human FAK.

Full name:

protein tyrosine kinase 2

Synonyms：

FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

SwissProt:

Q05397

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

119 kDa

WB Positive control:

Huvec cells and MCF7 cells lysates

WB Recommended dilution:

500-3000