Background:

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.

Applications:

WB, IHC

Name of antibody:

MED1

Immunogen:

Synthesized peptide derived from internal of human MED1.

Full name:

mediator complex subunit 1

Synonyms：

mediator complex subunit 1

SwissProt:

Q15648

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

168 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000