Background:

Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.

Applications:

ELISA, WB

Name of antibody:

NME6

Immunogen:

Fusion protein of human NME6

Full name:

NME/NM23 nucleoside diphosphate kinase 6

Synonyms：

NDK 6; NM23-H6; IPIA-ALPHA

SwissProt:

O75414

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

21 kDa

WB Positive control:

Mouse spleen and intestinum crassum tissue

WB Recommended dilution:

200-1000