Background:

This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

VPS54

Immunogen:

Fusion protein of human VPS54

Full name:

VPS54 subunit of GARP complex

Synonyms:

WR; HCC8; SLP-8p; VPS54L; hVps54L; PPP1R164

SwissProt:

Q9P1Q0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

25-100