Background:

SERPINB3(serpin peptidase inhibitor, clade B (ovalbumin), member 3), also known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). Human chromosome position 18q21.3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin. SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.

Applications:

ELISA, WB

Name of antibody:

SERPINB3

Immunogen:

Fusion protein of human SERPINB3

Full name:

serpin peptidase inhibitor, clade B (ovalbumin), member 3

Synonyms：

SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD

SwissProt:

P29508

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

45 kDa

WB Positive control:

Human fetal liver tissue

WB Recommended dilution:

500-2000