Background:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

Applications:

ELISA, IHC

Name of antibody:

SFN

Immunogen:

Full length fusion protein

Full name:

stratifin

Synonyms：

YWHAS

SwissProt:

P31947

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human breast cancer

IHC Recommend dilution:

25-100