Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

RPS6KA1

Immunogen:

Fusion protein of human RPS6KA1

Full name:

ribosomal protein S6 kinase, 90kDa, polypeptide 1

Synonyms：

RSK; HU-1; RSK1; MAPKAPK1A

SwissProt:

Q15418

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

83 kDa

WB Positive control:

K562 cells

WB Recommended dilution:

500-2000