Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.

Applications:

WB

Name of antibody:

MAPK1/MAPK3(Phospho-(Thr185/Tyr187)/(Thr202/Tyr204))

Immunogen:

Peptide sequence around phosphorylation site of (Thr185/Tyr187)/(Thr202/Tyr204) derived from Human MAPK1/MAPK3

Full name:

mitogen-activated protein kinase 1/3

Synonyms:

ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK

SwissProt:

P28482/P27361

WB Predicted band size:

43 kDa

WB Positive control:

NIH/3T3 cells lysates treated with IFNa

WB Recommended dilution:

500-1000