Background:

Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

Applications:

ELISA, WB, IHC

Name of antibody:

NHEJ1

Immunogen:

Synthetic peptide of human NHEJ1

Full name:

non-homologous end joining factor 1

Synonyms:

XLF

SwissProt:

Q9H9Q4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

33 kDa

WB Positive control:

PC-3 cell lysate

WB Recommended dilution:

200-1000