Background:

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Applications:

ELISA, IHC

Name of antibody:

GUCY1A1

Immunogen:

Fusion protein of human GUCY1A1

Full name:

guanylate cyclase 1 soluble subunit alpha 1

Synonyms:

GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A3

SwissProt:

Q02108

IHC positive control:

Human lung cancer and Human thyroid cancer

IHC Recommend dilution:

25-100