Background:

This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.

Applications:

WB, IHC

Name of antibody:

STMN1(Phospho-Ser62)

Immunogen:

Peptide sequence around phosphorylation site of Serine 62(R-R-K(p)-S-H) derived from Human STMN1.

Full name:

stathmin 1

Synonyms：

Lag; SMN; OP18; PP17; PP19; PR22; LAP18; C1orf215

SwissProt:

P16949

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

17 kDa

WB Positive control:

COS cells lysates treated with nocodazole

WB Recommended dilution:

500-1000