Background:

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Applications:

ELISA, WB, IHC

Name of antibody:

TGFBI

Immunogen:

Fusion protein of human TGFBI

Full name:

transforming growth factor beta induced

Synonyms:

CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1

SwissProt:

Q15582

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

75 kDa

WB Positive control:

Rat liver tissue lysate

WB Recommended dilution:

500-2000