Background:

The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions.

Applications:

ELISA, IHC

Name of antibody:

SLC4A1

Immunogen:

Synthetic peptide of human SLC4A1

Full name:

solute carrier family 4 (anion exchanger), member 1

Synonyms：

DI; FR; SW; WD; WR; AE1; WD1; BND3; EPB3; CD233; EMPB3; RTA1A

SwissProt:

P02730

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

15-50