Background:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm.

Applications:

WB, IHC

Name of antibody:

PTBP1

Immunogen:

Fusion protein of human PTBP1

Full name:

polypyrimidine tract binding protein 1

Synonyms：

PTB; PTB2; PTB3; PTB4; pPTB; HNRPI; PTB-1; PTB-T; HNRNPI; HNRNP-I

SwissProt:

P26599

IHC positive control:

Human prostate cancer and Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

57 kDa

WB Positive control:

Hela, hepg2 and HT-29 cell

WB Recommended dilution:

200-1000